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XIAP

X-linked inhibitor of apoptosis

Synonyme:
API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(331) Summary: This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]
  • Mouse(11798) X-linked inhibitor of apoptosis
  • Rat(63879) X-linked inhibitor of apoptosis
  • Zebrafish(373108) X-linked inhibitor of apoptosis
  • domestic cat(101090594) X-linked inhibitor of apoptosis
  • Horse(100060870) X-linked inhibitor of apoptosis
  • dog(442989) X-linked inhibitor of apoptosis
  • chicken(395280) X-linked inhibitor of apoptosis
  • domestic guinea pig(100715778) X-linked inhibitor of apoptosis
  • naked mole-rat(101715865) X-linked inhibitor of apoptosis
  • Domestic Rabbit(100328700) X-linked inhibitor of apoptosis
  • cow(281647) X-linked inhibitor of apoptosis
  • sheep(101116381) X-linked inhibitor of apoptosis

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ELISA

Produktnummer
Beschreibung
Spezies
Mouse Xiap / E3 Ubiquitin-protein Ligase XIAP ELISA Kit, ,
Spezies
mouse
Human XIAP ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Spezies
human
Rat Xiap / E3 Ubiquitin-protein Ligase XIAP ELISA Kit, ,
Spezies
rat

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Embelin, ≥98% (HPLC), powder,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-XIAP antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-XIAP Antibody, clone 3H4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, monkey, rat
Anwendung
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Monoclonal Anti-BIRC4 antibody produced in mouse, clone 1F4, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence

proximity ligation assay

western blot
Anti-phospho-XIAP (pSer87) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
western blot
Anti-phospho-XIAP (pSer87) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry

western blot

Proteins

Produktnummer
Beschreibung
Spezies
XIAP Active human, recombinant, expressed in baculovirus infected insect cells, ≥65% (SDS-PAGE),
Spezies
human
XIAP, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Xiap,
Spezies
mouse
MISSION® esiRNA, targeting human XIAP,
Spezies
human