SLC6A4
solute carrier family 6 (neurotransmitter transporter), member 4
Synonyme:
5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT
Spezies:
Human SLC6A4 (6532), Mouse Slc6a4 (15567), Rat Slc6a4 (25553), domestic guinea pig Slc6a4 (100135619), naked mole-rat Slc6a4 (101705584), Domestic Rabbit SLC6A4 (100340600), Domestic Rabbit SLC6A4 (100351801), cow SLC6A4 (282365), chicken SLC6A4 (404747), Horse SLC6A4 (100053721) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(6532) Summary: This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]
- Mouse(15567) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Rat(25553) solute carrier family 6 (neurotransmitter transporter), member 4
- domestic guinea pig(100135619) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- naked mole-rat(101705584) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Domestic Rabbit(100340600) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Domestic Rabbit(100351801) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- cow(282365) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- chicken(404747) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Horse(100053721) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- domestic cat(101091163) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- dog(491184) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
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Small Molecule - Antagonist
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Serotonin Transporter (N-terminal) antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot
Anti-Serotonin (5-HT) Transporter (602-622) Rabbit pAb, lyophilized, Calbiochem®,
Speziesreaktivität
mouse, rat
Anwendung
Anti-SLC6A4/5HTT/SERT antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
western blot
Anti-SLC6A4 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
bovine, human, mouse, rat
Anwendung
ELISA
flow cytometry
immunofluorescence
flow cytometry
immunofluorescence
Anti-SLC6A4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
Small Molecule - Inhibitor
Produktnummer
Beschreibung
Spezies
Fluoxetin -hydrochlorid -Lösung, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Sertraline hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
esiRNA
Produktnummer
Beschreibung
Spezies