MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
Synonyme:
ACTFS, HDMX, hdm2
Spezies:
Human MDM2 (4193), Mouse Mdm2 (17246), Rat Mdm2 (314856), Zebrafish mdm2 (30637), dog MDM2 (403693), domestic cat MDM2 (493939), cow MDM2 (540378), Horse MDM2 (100033891), chicken MDM2 (395609), domestic guinea pig Mdm2 (100724684) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(4193) Summary: This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
- Mouse(17246) transformed mouse 3T3 cell double minute 2
- Rat(314856) p53 E3 ubiquitin protein ligase
- Zebrafish(30637) transformed 3T3 cell double minute 2 homolog (mouse)
- dog(403693) Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
- domestic cat(493939) Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
- cow(540378) Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
- Horse(100033891) Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
- chicken(395609) Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
- domestic guinea pig(100724684) MDM2 oncogene, E3 ubiquitin protein ligase
- naked mole-rat(101724821) MDM2 oncogene, E3 ubiquitin protein ligase
- sheep(101104979) Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
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ELISA
Produktnummer
Beschreibung
Spezies
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-MDM2-Antikörper, Klon IF2, clone IF2, from mouse,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
western blot
Anti-MDM2 (Ab-2) Mouse mAb (2A10), liquid, clone 2A10, Calbiochem®,
Speziesreaktivität
human
Anwendung
Anti-MDM2-Antikörper, Klon IF2, Alexa Fluor™ 488-Konjugat, clone IF2, from mouse, ALEXA FLUOR™ 488,
Speziesreaktivität
human
Anwendung
immunocytochemistry
Anti-MDM2 Antibody, clone 2A10, clone 2A10, from mouse,
Speziesreaktivität
human
Anwendung
immunoprecipitation (IP)
western blot
western blot
Monoclonal Anti-MDM2 antibody produced in mouse, ~2 mg/mL, clone MD-219, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
mouse
Anwendung
ELISA
flow cytometry
immunocytochemistry
microarray
western blot
flow cytometry
immunocytochemistry
microarray
western blot