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ITGAV

integrin, alpha V

Synonyme:
CD51, MSK8, VNRA, VTNR
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3685) Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]
  • Mouse(16410) integrin alpha V
  • Rat(296456) integrin, alpha V
  • sheep(443143) integrin, alpha V
  • Domestic Rabbit(100008956) integrin, alpha V
  • domestic guinea pig(100728575) integrin, alpha V
  • naked mole-rat(101717672) integrin, alpha V
  • Zebrafish(100151255) integrin, alpha V
  • cow(281875) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • Horse(100068706) integrin, alpha V
  • domestic cat(101085820) integrin, alpha V
  • dog(488437) integrin, alpha V
  • chicken(396420) integrin, alpha V

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Small Molecule - Antagonist

Product Number
Beschreibung
Spezies
Gly-Arg-Gly-Asp-Ser-Pro-Lys, ≥97% (HPLC),
Spezies
human

Antibodies

Product Number
Beschreibung
Speziesreaktivität
Anwendung
Anti-Integrin-α-V-β-6-Antikörper, Klon 10D5, azidfrei, clone 10D5, Chemicon®, from mouse,
Speziesreaktivität
human, mouse, rat
Anwendung
flow cytometry
immunoprecipitation (IP)
Anti-Integrin αVβ3 Antibody, clone LM609, clone LM609, Chemicon®, from mouse,
Speziesreaktivität
avian, bovine, canine, chicken, human, monkey, pig, rabbit
Anwendung
flow cytometry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)
Anti-Integrin αV Antibody, clone LM142, ,
Speziesreaktivität
human
Anwendung
flow cytometry
immunofluorescence

immunohistochemistry

neutralization
Anti-Integrin αV-Antikörper, Klon LM142, ascites fluid, clone LM142, Chemicon®,
Speziesreaktivität
human
Anwendung
immunohistochemistry
immunoprecipitation (IP)
Anti-Integrin-αVβ3-Antikörper, Klon LM609, azidfrei, clone LM609, Chemicon®, from mouse,
Speziesreaktivität
avian, bovine, canine, chicken, human, monkey, pig, rabbit
Anwendung
flow cytometry
immunohistochemistry

immunoprecipitation (IP)

Proteins

Product Number
Beschreibung
Spezies
Human Integrin αVβ3, Octyl-β-D-glucopyranoside Formulation, ,
Spezies
human
Human Integrin αVβ3 Protein, Triton X-100 Formulation, ,
Spezies
human

esiRNA

Product Number
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Itgav,
Spezies
mouse
MISSION® esiRNA, targeting human ITGAV,
Spezies
human