ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
Synonyme:
BDPLT16, BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3
Spezies:
Human ITGA2B (3674), Mouse Itga2b (16399), Rat Itga2b (685269), Zebrafish itga2b (445380), dog ITGA2B (403789), domestic cat ITGA2B (101100930), cow ITGA2B (515011), Horse ITGA2B (100009697), sheep ITGA2B (101115719), domestic guinea pig Itga2b (100727374)
UniProtKB-ID:
Gen-ID:
- Human(3674) Summary: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
- Mouse(16399) integrin alpha 2b
- Rat(685269) integrin, alpha 2B
- Zebrafish(445380) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)
- dog(403789) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- domestic cat(101100930) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- cow(515011) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- Horse(100009697) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- sheep(101115719) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- domestic guinea pig(100727374) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
- naked mole-rat(101714332) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
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Small Molecule - Antagonist
Produktnummer
Beschreibung
Spezies
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Integrin αIIb Mouse mAb (283.16B7), liquid, clone 283.16B7, Calbiochem®,
Speziesreaktivität
human
Anwendung
Anti-Platelet Antibody, clone PAC-1, clone PAC-1, from mouse,
Speziesreaktivität
human
Anwendung
ELISA
dot blot
flow cytometry
radioimmunoassay
western blot
dot blot
flow cytometry
radioimmunoassay
western blot
Anti-Integrin α2b (CD41) antibody, Mouse monoclonal, clone PM6/248, purified from hybridoma cell culture,
Speziesreaktivität
baboon, human
Anwendung
flow cytometry
immunoprecipitation (IP)
immunoprecipitation (IP)
Anti-CD41/ITGA2B antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
western blot
Monoclonal Anti-CD41a antibody produced in mouse, clone HIP8, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human, nonhuman primates
Anwendung
flow cytometry
Small Molecule - Inhibitor
Produktnummer
Beschreibung
Spezies