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GFI1

growth factor independent 1 transcription repressor

Synonyme:
GFI-1, GFI1A, SCN2, ZNF163
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(2672) Summary: This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14581) growth factor independent 1
  • Rat(24388) growth factor independent 1 transcription repressor
  • chicken(429088) growth factor independent 1 transcription repressor
  • domestic cat(100127020) growth factor independent 1 transcription repressor
  • cow(100139952) growth factor independent 1 transcription repressor
  • dog(490156) growth factor independent 1 transcription repressor
  • sheep(101116880) growth factor independent 1 transcription repressor
  • naked mole-rat(101715410) growth factor independent 1 transcription repressor
  • domestic guinea pig(100716876) growth factor independent 1 transcription repressor

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-GFI1 antibody produced in mouse, clone 3G8, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-GFI1 (AB2) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
bovine, human, pig, rat
Anwendung
western blot
Anti-Growth Factor Independence-1 antibody, Mouse monoclonal, clone 2.5D.17, purified from hybridoma cell culture,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
microarray

western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human GFI1,
Spezies
human