CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
Synonyme:
CP2B, CYP1, CYP1alpha, CYP27B, P450c1, PDDR, VDD1, VDDR, VDDRI, VDR
Spezies:
Human CYP27B1 (1594), Mouse Cyp27b1 (13115), Rat Cyp27b1 (114700), domestic cat CYP27B1 (100750221), dog CYP27B1 (481133), Horse CYP27B1 (100034100), cow CYP27B1 (539630)
UniProtKB-ID:
Gen-ID:
- Human(1594) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I. [provided by RefSeq, Jul 2008]
- Mouse(13115) cytochrome P450, family 27, subfamily b, polypeptide 1
- Rat(114700) cytochrome P450, family 27, subfamily b, polypeptide 1
- domestic cat(100750221) cytochrome P450, family 27, subfamily B, polypeptide 1
- dog(481133) cytochrome P450, family 27, subfamily B, polypeptide 1
- Horse(100034100) cytochrome P450, family 27, subfamily B, polypeptide 1
- cow(539630) cytochrome P450, family 27, subfamily B, polypeptide 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CYP27B1 Antibody, from rabbit, purified by affinity chromatography,
Speziesreaktivität
chimpanzee, human, mouse, rat
Anwendung
immunohistochemistry
western blot
western blot
esiRNA
Produktnummer
Beschreibung
Spezies