BIN1
bridging integrator 1
Synonyme:
AMPH2, AMPHL, SH3P9
Spezies:
Human BIN1 (274), Mouse Bin1 (30948), Rat Bin1 (117028), Zebrafish bin1 (447863), Horse BIN1 (100052213), cow BIN1 (614576), domestic cat BIN1 (101097908), fruit fly Bin1 (41965), dog BIN1 (483870), chicken BIN1 (424228) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(274) Summary: This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq, Sep 2011]
- Mouse(30948) bridging integrator 1
- Rat(117028) bridging integrator 1
- Zebrafish(447863) bridging integrator 1
- Horse(100052213) bridging integrator 1
- cow(614576) bridging integrator 1
- domestic cat(101097908) bridging integrator 1
- fruit fly(41965) Bicoid interacting protein 1
- dog(483870) bridging integrator 1
- chicken(424228) bridging integrator 1
- domestic guinea pig(100722858) bridging integrator 1
- naked mole-rat(101723039) bridging integrator 1
- sheep(101119119) bridging integrator 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-BIN1 antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-BIN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-BIN1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
western blot
western blot
Monoclonal Anti-BIN1, (C-terminal) antibody produced in mouse, clone 2C7, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
western blot
Anti-Bin1 Antibody, clone 99D, clone 99D, Upstate®, from mouse,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot