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ANPEP

alanyl (membrane) aminopeptidase

Synonyme:
APN, CD13, GP150, LAP1, P150, PEPN
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(290) Summary: Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq, Jul 2008]
  • Mouse(16790) alanyl (membrane) aminopeptidase
  • Rat(81641) alanyl (membrane) aminopeptidase
  • chicken(395667) alanyl (membrane) aminopeptidase
  • domestic cat(493785) alanyl (membrane) aminopeptidase
  • Horse(100050397) alanyl (membrane) aminopeptidase
  • cow(404191) alanyl (membrane) aminopeptidase
  • dog(403913) alanyl (membrane) aminopeptidase
  • sheep(101104860) alanyl (membrane) aminopeptidase
  • Domestic Rabbit(100009167) alanyl (membrane) aminopeptidase
  • domestic guinea pig(100727522) alanyl (membrane) aminopeptidase
  • naked mole-rat(101706035) alanyl (membrane) aminopeptidase

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ELISA

Produktnummer
Beschreibung
Spezies
Human Aminopeptidase N ELISA, for serum, plasma and cell culture supernatants,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-ANPEP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry

western blot
Milli-Mark® Anti-CD13-FITC Antibody, clone WM-47, clone WM-47, Milli-Mark®, from mouse,
Speziesreaktivität
human
Anwendung
flow cytometry
Anti-CD13 antibody, Rabbit monoclonal, clone SP182, recombinant, expressed in proprietary host, affinity isolated antibody,
Speziesreaktivität
human, pig, rabbit
Anwendung
flow cytometry
immunohistochemistry
Monoclonal Anti-CD13 antibody produced in mouse, clone WM15, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human, nonhuman primates
Anwendung
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Anti-APN/CD13 Antibody, clone 1D20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, rat
Anwendung
affinity binding assay
flow cytometry

immunohistochemistry

western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Actinonin, ,
Spezies
human
N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucin, 97%,
Spezies
human, mouse, rat
Flavon, ≥99.0%,
Spezies
human, rat, mouse

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human ANPEP,
Spezies
human
MISSION® esiRNA, targeting mouse Anpep,
Spezies
mouse