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V800345

1,2-Propanediol

Name: 1,2-Propanediol
Brand: VETEC

LR, ≥99%

Sinónimos:

Propylene glycol

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About This Item

Fórmula lineal:

CH₃CH(OH)CH₂OH

Número de CAS:

57-55-6

Peso molecular:

76.09

Beilstein/REAXYS Number:

1340498

EC Number:

200-338-0

MDL number:

MFCD00064272

UNSPSC Code:

12191502

PubChem Substance ID:

329829330

grade

Quality Level

100

vapor density

2.62 (vs air)

vapor pressure

0.08 mmHg ( 20 °C)

product line

Vetec^™

assay

≥99%

form

viscous liquid

autoignition temp.

779 °F

expl. lim.

12.5 %

refractive index

n20/D 1.432 (lit.)

bp

187 °C (lit.)

mp

−60 °C (lit.)

density

1.036 g/mL at 25 °C (lit.)

functional group

hydroxyl

SMILES string

CC(O)CO

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

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Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

217.4 °F - closed cup

flash_point_c

103 °C - closed cup

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Expression and inducibility of antigens in severe combined immunodeficient mice recognized by human anti-P450 antibodies.

R S Rajasenan et al.

Toxicology and applied pharmacology, 135(1), 89-99 (1995-11-01)

Engrafting components of human immune systems in severe combined immunodeficient (SCID) mice has been utilized to investigate the pathogenesis of several human autoimmune diseases and may provide a model for studying idiosyncratic drug toxicity. The purpose of this investigation was

Acetone metabolism in humans during diabetic ketoacidosis.

G A Reichard et al.

Diabetes, 35(6), 668-674 (1986-06-01)

Plasma acetone turnover rates were measured with the primed continuous infusion of 2-[14C]acetone in patients with moderate to severe diabetic ketoacidosis. Plasma acetone turnover rates ranged from 1.52 to 15.9 mumol X kg-1 X min-1 (108-1038 mumol X 1.73 m-2

Terpenes in propylene glycol as skin-penetration enhancers: permeation and partition of haloperidol, Fourier transform infrared spectroscopy, and differential scanning calorimetry.

H K Vaddi et al.

Journal of pharmaceutical sciences, 91(7), 1639-1651 (2002-07-13)

The respective alcoholic terpenes carvacrol, linalool, and alpha-terpineol were used at 5% w/v in propylene glycol (PG) to increase the in vitro permeation of haloperidol (HP) through human skin. The possible enhancement mechanism was then elucidated with HP-stratum corneum (SC)

In vitro iontophoresis of R-apomorphine across human stratum corneum. Structure-transport relationship of penetration enhancement.

Gai Ling Li et al.

Journal of controlled release : official journal of the Controlled Release Society, 84(1-2), 49-57 (2002-10-26)

To achieve a therapeutical effect of the anti-Parkinson's drug R-apomorphine via iontophoresis delivery, enhancement strategies in vitro were explored using three structurally related enhancers, lauric acid (LA), dodecyltrimethylammonium bromide (DTAB) and Laureth-3 oxyethylene ether (C(12)EO(3)). Human stratum corneum and shed

LC analysis of benzophenone-3: II application to determination of 'in vitro' and 'in vivo' skin penetration from solvents, coarse and submicron emulsions.

C Fernandez et al.

Journal of pharmaceutical and biomedical analysis, 24(1), 155-165 (2000-12-07)

The aim of this study was to determine the skin penetration of benzophenone-3 in vitro and in vivo in order to investigate a possible influence of formulation. Six different vehicles, three solvents and three different emulsion types were evaluated in

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