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1078507

USP

Bupivacaine hydrochloride

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

Bupivacaine hydrochloride monohydrate, 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide hydrochloride hydrate

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About This Item

Fórmula empírica (notación de Hill):
C18H28N2O · HCl · H2O
Número de CAS:
73360-54-0
Peso molecular:
342.90
MDL number:
MFCD00941462
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

bupivacaine

manufacturer/tradename

USP

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[Cl-].[N+H]1(C(CCCC1)C(=O)Nc2c(cccc2C)C)CCCC.O

InChI

1S/C18H28N2O.ClH.H2O/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3;;/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21);1H;1H2

InChI key

HUCIWBPMHXGLFM-UHFFFAOYSA-N

Categorías relacionadas

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Bupivacaine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Bupivacaine Hydrochloride Injection
  • Bupivacaine Hydrochloride in Dextrose Injection
  • Bupivacaine Hydrochloride and Epinephrine Injection
  • Fentanyl Citrate and Bupivacaine Hydrochloride Compounded Injection
  • Ropivacaine Hydrochloride

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

Referencia del producto
Descripción
Precios

Y0000088

Bupivacaine impurity B, European Pharmacopoeia (EP) Reference Standard

Y0000089

Bupivacaine impurity E, European Pharmacopoeia (EP) Reference Standard

Y0001575

2,6-Dimethylaniline, European Pharmacopoeia (EP) Reference Standard

B1160000

Bupivacaine hydrochloride, European Pharmacopoeia (EP) Reference Standard

1078529

Bupivacaine Related Compound B, United States Pharmacopeia (USP) Reference Standard

1078518

Bupivacaine Related Compound A, United States Pharmacopeia (USP) Reference Standard

PHR1738

Bupivacaine Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1756

Bupivacaine Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

BP479

Bupivacaine hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR9084

(S)-Bupivacaine, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

PHR9147

N-(2,6-Dimethylphenyl)pyridine-2-carboxamide, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Bupivacaine Hydrochloride and Epinephrine Injection
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 612-612 (2018)
I Demirel et al.
European review for medical and pharmacological sciences, 18(7), 1067-1072 (2014-04-26)
Just as hip prosthesis, most of the patients undergoing orthopedic lower extremity surgery (OLES) belong to the advanced age group. Sciatic nerve block combined with psoas compartment block is used as a technique alternative to central neuraxial block and GA.
Deborah S Keller et al.
Diseases of the colon and rectum, 57(11), 1290-1297 (2014-10-07)
Superior early pain control has been suggested with transversus abdominis plane blocks, but evidence-based recommendations for transversus abdominis plane blocks and their effects on patient outcomes are lacking. The aim of this study was to determine whether transversus abdominis plane
Nurcan Yavuz et al.
Pakistan journal of medical sciences, 30(6), 1286-1292 (2015-02-13)
Total knee arthroplasty (TKA) is associated with considerable postoperative pain. We compared the effects of intraoperative intraarticular levobupivacaine and bupivacaine on postoperative analgesia and analgesic consumption after total knee arthroplasty. Sixty ASA (American Society of Anesthesiologists) physical status II-III, 18-75
Francesca Taraballi et al.
Journal of pharmaceutical sciences, 103(11), 3724-3732 (2014-10-01)
Acute pain remains a tremendous clinical and economic burden, as its prevalence and common narcotic-based treatments are associated with poorer outcomes and higher costs. Multimodal analgesia portends great therapeutic promise, but rarely allows opioid sparing, and new alternatives are necessary.
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