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Merck

21104

Supelco

GC Stationary Phase

phase OV-1, bottle of 10 g

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About This Item

UNSPSC Code:
23151817

agency

meets requirements for USP G2

packaging

bottle of 10 g

parameter

100-350 °C temp. range

technique(s)

gas chromatography (GC): suitable

matrix active group

OV-1 phase

solubility

chloroform, toluene: soluble

column type

packed GC

General description

GC methods are divided into two classes depending on the nature of stationary phases; gas-solid chromatography (GSC) and gas-liquid chromatography (GLC). GSC has solid adsorptive material and solute particles are removed from mobile phase by electrostatic forces. GLC has a thin layer of liquid coated or bonded on the surface of an inert particle or on the walls of the column where solute particles are retained in the liquid phase based on their partition coefficients. The primary necessity of a stationary phase is to provide sample separation sustaining phase integrity over a reasonable period of time. It should be stable for the chemical and thermal changes. Selectivity, peak symmetry, analysis time, degree of separation, peak tailing are a few parameters that should be considered before choosing a stationary phase. OV-1 is suitable for the separation of drugs, alkaloids, phenols and steroids.
Synthesized specifically to be purer, of narrow molecular weight range, and without trace catalysts or impurities for use as a GC stationary phase.

Application

OV-1 is suitable as stationary phase for monitoring the urinary excretion in man for pentachlorophenol (PCP) and PCP conjugated to glucuronic acid using gas chromatography with electron capture detection (GC/ECD).

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

214.0 °F - closed cup

flash_point_c

101.1 °C - closed cup

ppe

Eyeshields, Gloves


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S Uhl et al.
Archives of toxicology, 58(3), 182-186 (1986-02-01)
Pentachlorophenol (PCP) was given orally to three volunteers at single doses of 3.9, 4.5, 9, and 18.8 mg. Daily urinary excretion of PCP and PCP conjugated to glucuronic acid was monitored using gas chromatography with electron capture detection (GC/ECD). Based
James P. Lodge, Jr.
Methods of Air Sampling and Analysis, 98-98 (1988)
David B. Troy, Paul Beringer
Remington: The Science and Practice of Pharmacy, 605-605 (2006)

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