SML3508

Intepirdine

≥98% (HPLC)

• Sinónimos: 3-(Phenylsulfonyl)-8-(1-piperazinyl)quinoline, 3-Phenylsulfonyl-8-(piperazin-1-yl)quinoline, GSK 742457, RVT 101, SB-742457
• Fórmula empírica (notación de Hill): C₁₉H₁₉N₃O₂S
• Número de CAS: 607742-69-8
• Peso molecular: 353.44
• MDL number: MFCD12828872
• UNSPSC Code: 51111800
• UNSPSC Code: 12352200
• NACRES: NA.21

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=S(C1=CC=CC=C1)(C2=CC3=C(N=C2)C(N4CCNCC4)=CC=C3)=O

Descripción

Biochem/physiol Actions

Intepirdine (SB-742457) is a brain blood barrier penetrant, orally available, potent and selective serotonin receptor 6 (5-HT6) receptor antagonist that potentiate cognitive and the behavioral abnormalities of AD in laboratory set up. Intepirdine has failed to demonstrate statistically significant impact on cognition or dementia in phase III trials. Intepirdine promotes satiety.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable