SML3345

LSL 60101

≥98% (HPLC)

• Sinónimos: 2-(1-Benzofuran-2-yl)-1H -imidazole, 2-(2-Benzofuranyl)-1H -imidazole (ACI), Garsevil, LSL60101
• Fórmula empírica (notación de Hill): C₁₁H₈N₂O
• Número de CAS: 150985-54-9
• Peso molecular: 184.19
• MDL number: MFCD17292409
• UNSPSC Code: 51111800
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: [nH]1c(ncc1)c2[o]c3c(c2)cccc3
• InChI: 1S/C11H8N2O/c1-2-4-9-8(3-1)7-10(14-9)11-12-5-6-13-11/h1-7H,(H,12,13)
• InChI key: VBFQIUOSXHUWCT-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

LSL 60101 is an orally available, potent and selective I2 imidazoline receptor ligand that induces morphological/biochemical changes in astroglia and exhibits neuroprotective activity. LSL 60101 decreases neuroinflammation and reverses cognitive deficits and impaired social behavior in 5XFAD mice Alzheimer’s model.

Orally available, potent and selective I2 imidazoline receptor ligand that exhibits neuroprotective activity

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable