SML1263

Arylquin 1

≥98% (HPLC)

• Sinónimos: 3-(2-Fluorophenyl)-N7,N7-dimethylquinoline-2,7-diamine)
• Fórmula empírica (notación de Hill): C₁₇H₁₆FN₃
• Número de CAS: 1630743-73-5
• Peso molecular: 281.33
• MDL number: MFCD28580129
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825755
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: , white to yellow to light brown
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: NC1=NC2=CC(N(C)C)=CC=C2C=C1C3=CC=CC=C3F
• InChI: 1S/C17H16FN3/c1-21(2)12-8-7-11-9-14(17(19)20-16(11)10-12)13-5-3-4-6-15(13)18/h3-10H,1-2H3,(H2,19,20)
• InChI key: RHAQINSYYSNKKI-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

Arylquin 1 is a potent secretagogue of the tumor suppressor protein prostate apoptosis response-4 (Par-4), selectively inducing apoptosis in a variety of cancer cells. Arylquin 1 acts by binding to vimentin, displacing Par-4 from vimentin for secretion. Arylquin 1 produced a dose-dependent secretion of Par-4 at nanomolar concentrations.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable