SML1141

Solasodine

≥95% (HPLC)

• Sinónimos: (-)-Solasodine, (3β,22α,25R)-Spirosol-5-en-3-ol, NSC 178260, NSC 179187, Purapuridine, Solancarpidine, Solasod-5-en-3β-ol, Solasod-5-en-3β-ol (7CI,8CI), Solasodin
• Fórmula empírica (notación de Hill): C₂₇H₄₃NO₂
• Número de CAS: 126-17-0
• Peso molecular: 413.64
• EC Number: 204-774-2
• UNSPSC Code: 12352200
• NACRES: NA.77

Propiedades

• assay: ≥95% (HPLC)
• form: powder
• optical activity: [α]/D -88 to -98°, c = 0.2 in methanol
• color: white to beige
• solubility: DMSO: 0.5 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: C[C@@H]1[C@]2(NC[C@H](C)CC2)O[C@@]3([H])C[C@@]4([H])[C@]5([H])CC=C6C[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)[C@]31[H]
• InChI: 1S/C27H43NO2/c1-16-7-12-27(28-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(29)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28-29H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1
• InChI key: KWVISVAMQJWJSZ-VKROHFNGSA-N

Descripción

Application

Solasodine has been used in viability assays.

Biochem/physiol Actions

Solasodine is a neuroprotective antioxidant glycoalkaloid of Solanum species. Solasodine increases superoxide dismutase (SOD), catalase (CAT),and glutathione (GSH) levels, while reducing lipid peroxidation (LPO) and nitric oxide (NO) levels in the brains of ischemia/reperfusion (I/R)-injury model in rats. Also, Solasonine displayed multiple activities including, anti-cancer and leishmanicidal activities.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable