SAB5702986

Anti-Dystrophin Antibody

rabbit monoclonal, 10G10K7

• Sinónimos: BMD, CMD3B, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85
• UNSPSC Code: 12352203
• NACRES: NA.46

Propiedades

• product name: Anti-Dystrophin Antibody, clone 10G10K7, Rabbit Monoclonal,
• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 10G10K7, monoclonal
• form: liquid
• species reactivity: mouse, rat
• concentration: 0.5mg/mL
• technique(s): immunofluorescence: 1:50 - 1:200; immunohistochemistry: 1:50 - 1:200
• color: colorless
• isotype: IgG
• immunogen sequence: LESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM
• UniProt accession no.: P11532
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... DMD(1756)

Descripción

General description

This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 3586-3685 of human Dystrophin (P11532).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

IHC, IF/ICC

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1