SAB5700427

Anti-Phospho-STK11-T189 antibody produced in rabbit

• Sinónimos: LKB1, PJS, STK11, hLKB1
• UNSPSC Code: 12352203

Propiedades

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 45; 48
• species reactivity: human
• concentration: 2.39 mg/ml
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: Q15831
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pThr189)
• Gene Information: human ... STK11(6794)

Descripción

General description

This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Immunogen

A synthetic phosphorylated peptide around T189 of human STK11 (NP_000446.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable