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Key Documents

SAB5600116

Sigma-Aldrich

Anti-HA-Tag antibody, Rabbit Monoclonal

recombinant, expressed in HEK 293 cells, clone RM305, purified immunoglobulin

Sinónimos:

Human influenza hemagglutinin amino acids 98-106

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

recombinant

expressed in HEK 293 cells

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

RM305, monoclonal
recombinant monoclonal

form

buffered aqueous glycerol solution

technique(s)

flow cytometry: 0.1-1 μg/mL
immunocytochemistry: 0.1-1 μg/mL
immunohistochemistry: 0.01-0.5 μg/mL
immunoprecipitation (IP): 0.5-2 μg/mL
western blot: 0.1-1 μg/mL

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

The hemagglutinin (HA) gene is mapped to segment 4 of Influenza B viral genome. HA is a dominant antigen present on the influenza viral surface. It is a homotrimer and each monomer is produced as a single polypeptide.

Specificity

This antibody reacts to recombinant proteins containing a HA-Tag fused to either the amino or carboxy terminus. No cross reactivity with other endogenous protein.

Immunogen

A peptide corresponding to HA-tag (Human influenza hemagglutinin amino acids 98-106).

Application

Anti-HA-Tag antibody, Rabbit Monoclonal has been used in western blotting.

Biochem/physiol Actions

Hemagglutinin (HA) regulates membrane fusion and receptor-binding functions during viral entry and infection. The virus gains entry into the host cell via endocytosis and successive membrane fusion mediated by the HA antigen. HA plays a crucial role in viral pathogenesis and host response to viral infection.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Entry, Replication, Immune Evasion, and Neurotoxicity of Synthetically Engineered Bat-Borne Mumps Virus
Kruger N, et al.
Cell Reports, 25(2), 312-320 (2018)
On the origin of the human influenza virus subtypes H2N2 and H3N2.
Scholtissek C, et al.
Virology, 87(1), 13-20 (1978)
Structure and receptor specificity of the hemagglutinin from an H5N1 influenza virus.
Stevens J, et al.
Science, 312(5772), 404-410 (2006)
Bryan A Copits et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(20), 7334-7340 (2011-05-20)
Auxiliary proteins modify the biophysical function and pharmacological properties of ionotropic glutamate receptors and likely are important components of receptor signaling complexes in vivo. The neuropilin and tolloid-like proteins (NETO) 1 and NETO2, two closely related CUB domain-containing integral membrane

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