SAB4700325
Monoclonal Anti-HLA-G-PE , (C-terminal) antibody produced in mouse
clone 5A6G7, purified immunoglobulin, buffered aqueous solution
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About This Item
Productos recomendados
biological source
mouse
Quality Level
conjugate
phycoerythrin (R-PE) conjugate
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
5A6G7, monoclonal
form
buffered aqueous solution
species reactivity
human
concentration
0.1 mg/mL
technique(s)
flow cytometry: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
human ... HLA-G(3135)
Categorías relacionadas
General description
The antibody 5A6G7 allows to discriminate between soluble HLA-G protein yielded by shedding from membrane-bound HLA-G forms that do not contain the intron 4-encoded epitope and soluble HLA-G5/HLA-G6 produced from intron 4-retaining alternatively spliced mRNAs. HLA-G belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of trophoblast cells.
Immunogen
C-terminal amino acid sequence (22-mer) of soluble HLA-G5 and HLA-G6 proteins coupled to ovalbumin
Application
The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 10 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Journal of virology, 79(24), 15226-15237 (2005-11-25)
HLA-G is a nonclassical human major histocompatibility complex class I molecule. It may promote tolerance, leading to acceptance of the semiallogeneic fetus and tumor immune escape. We show here that two viruses-herpes simplex virus type 1 (HSV-1), a neuronotropic virus
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