SAB4504393

Anti-phospho-eNOS (pSer¹¹⁷⁶) antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-ECNOS, Anti-eNOS
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 133 kDa
• species reactivity: rat, human, mouse
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:20000; western blot: 1:500-1:1000
• NCBI accession no.: P29474
• UniProt accession no.: P29474
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer1176)
• Gene Information: human ... NOS3(4846)

Descripción

General description

Nitric oxide synthase 3 (NOS3), also known as endothelial nitric oxide synthase (eNOS), is encoded by the gene mapped to human chromosome 7q35-36. The gene consists of 26 exons.

Immunogen

The antiserum was produced against synthesized peptide derived from human eNOS around the phosphorylation site of Ser1176.

Immunogen Range: 1144-1193

Biochem/physiol Actions

Nitric oxide synthase 3 (NOS3) has been studied as a modulator of vascular function and is involved in the production of nitric oxide. Defects in the enzyme expression have been shown to be associated with coronary artery disease.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable