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Merck
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SAB3701439

Sigma-Aldrich

Monoclonal Anti-IL-17A antibody produced in mouse

clone 4H1524.1, purified immunoglobulin

Sinónimos:

Anti-Cytotoxic T-Lymphocyte-associated Antigen 8, Anti-IL-17, Anti-IL-17A, Anti-Interleukin-17, Anti-Interleukin-17A

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

4H1524.1, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

flow cytometry: suitable
western blot: suitable

isotype

IgG2b

UniProt accession no.

Q16552

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... IL17A(3605)

Specificity

Anti-Human IL-17A (MOUSE) Monoclonal Antibody was purified from concentrated tissue culture supernate by Protein G chromatography followed by extensive dialysis against the buffer stated above. This antibody is specific for human IL-17A protein. A BLAST analysis was used to suggest cross-reactivity with IL-17A from human sources based on 100% homology with the immunizing sequence. Cross-reactivity with IL-17A from other sources has not been determined.

Immunogen

Mature full length recombinant human IL-17A produced in E.coli followed by hybridoma development.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01% (w/v) Sodium Azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Referencia del producto
Descripción
Precios

Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
27357

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Jinho Kim et al.
Molecular brain, 14(1), 11-11 (2021-01-15)
The number of young adult patients with major depression, one of the most common mental disorders, is gradually increasing in modern society. Stressful experiences in early life are considered one of the risk factors for chronic depressive symptoms, along with
Sen Liu et al.
The Prostate, 80(10), 764-776 (2020-05-02)
Aging is the most important risk factor for prostate cancer (PCa), but how age contributes to PCa is poorly understood. Aging is characterized by low-grade systemic inflammation (i.e., inflammaging) that is often attributed to the progressive activation of immune cells
Weijie Ouyang et al.
Investigative ophthalmology & visual science, 62(1), 25-25 (2021-01-26)
To evaluate the role of CD4+ T helper cells in benzalkonium chloride (BAC)-induced ocular surface disorder in C57BL/6 mice. Topical 0.075% BAC was applied twice daily in C57BL/6 mice for 7 consecutive days; PBS-treated and untreated mice served as controls.
Jeremy S Schaefer et al.
Gene, 549(1), 134-140 (2014-07-27)
Roquin-1, a RING finger E3 ubiquitin ligase, functions as a modulator of inflammation; however, nothing is known about how Rc3h1 expression is regulated. Here, we describe an opposing relationship between Roquin-1 and the IL-17 proinflammatory cytokine by demonstrating that enforced
Bara Sarraj et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(33), 12145-12150 (2014-08-06)
Selectin-selectin ligand interactions mediate the initial steps in leukocyte migration, an integral part of immune responses. Fucosyltransferase-VII (FucT-VII), encoded by Fut7, is essential for biosynthesis of selectin ligands. In an established model of cardiac allograft vasculopathy and chronic rejection, Fut7(-/-)
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