SAB2701977

Anti-DBH antibody produced in rabbit

• Sinónimos: DBM
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: polyclonal
• form: liquid
• mol wt: 69 kDa
• species reactivity: mouse, human, rat
• concentration: 1 mg/mL
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:1,000; western blot: 1:500-1:3,000
• UniProt accession no.: P09172
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... DBH(1621)

Descripción

General description

Dopamine-β-hydroxylase (DBH) is found in the nuclei of noradrenergic and dopaminergic neurons. The DBH gene is mapped on the human chromosome at 9q34.2.

Immunogen

Recombinant fragment corresponding to a region within amino acids 8 and 320 of Dopamine beta Hydroxylase (Uniprot ID#P09172)

Application

Anti-DBH antibody produced in rabbit has been used in immunohistochemistry (1:200) (1:1000).

Biochem/physiol Actions

Dopamine-β-hydroxylase (DBH) protein plays a role in the conversion of dopamine to noradrenaline. This protein is implicated in various disorders such as Huntington′s chorea, hypertension, Parkinson′s, and smoking disorders. DBH protein is also implicated in heart failure and mental disorders like depression, Tourette syndrome, and schizophrenia. Lower levels of DHB plasma are seen in patients with bipolar disorders and unipolar psychotic depression. Higher levels of DBH plasma are observed in patients with severe depression.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H317,H412
• pcodes: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Hazard Classifications: Aquatic Chronic 3 - Skin Sens. 1
• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable