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SAB2501087

Anti-Uncoupling Protein 2/UCP2 antibody produced in goat

Name: Anti-Uncoupling Protein 2/UCP2 antibody produced in goat
Brand: SIGMA

affinity isolated antibody, buffered aqueous solution

Sinónimos:

Anti-SLC25A8, Anti-UCPH, Anti-Uncoupling protein 2

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, rat

technique(s)

immunofluorescence: suitable
indirect ELISA: suitable
western blot: suitable

UniProt accession no.

P70406

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... UCP2(7351)

Categorías relacionadas

Primary Antibodies

General description

Uncoupling protein 2 (UCP2) is an inner mitochondrial membrane protein. It expressed in various regions of the brain. In non-human primates, it is present in the hypothalamic nuclei, pituitary gland, brainstem, ventral tegmental area and substantia nigra. It is located on human chromosome 11q13.

Immunogen

Peptide with sequence C-DSVKQFYTKGSEH from the internal region of the protein sequence according to NP_003346.2.

Application

Anti-uncoupling protein 2/UCP2 antibody has been used in immunoblotting.

Biochem/physiol Actions

Uncoupling protein 2 (UCP2) controls energy metabolism and decreases the production of reactive oxygen species and guards against reperfusion damage. It plays a vital role in uncoupling electron transport from adenosine triphosphate (ATP) formation.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Physical exercise improves brain cortex and cerebellum mitochondrial bioenergetics and alters apoptotic, dynamic and auto (mito) phagy markers

Marques A I, et al.

Neuroscience, 301(8), 480-495 (2015)

The UCP2-866G/A Polymorphism Could be Considered as a Genetic Marker of Different Functional Prognosis in Ischemic Stroke After Recanalization

Cicuendez I D M, et al.

Neuromolecular Medicine, 19(4), 571-578 (2017)

Uncoupling protein 2 region on chromosome 11q13 is not linked to markers of obesity in familial type 2 diabetes

Elbein S C, et al.

Diabetes, 46(12), 2105-2108 (1997)

Maternal high-fat high-sucrose diet and gestational exercise modulate hepatic fat accumulation and liver mitochondrial respiratory capacity in mothers and male offspring.

Jelena Stevanović-Silva et al.

Metabolism: clinical and experimental, 116, 154704-154704 (2021-01-10)

Maternal high-caloric nutrition and related gestational diabetes mellitus (GDM) are associated with a high-risk for developing metabolic complications later in life and in their offspring. In contrast, exercise is recognized as a non-pharmacological strategy against metabolic dysfunctions associated to lifestyle

Uncoupling protein 2 haplotype does not affect human brain structure and function in a sample of community-dwelling older adults

Heise, et al.

PLoS ONE, 12(8), e0181392-e0181392 (2017)

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