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SAB1305560

Sigma-Aldrich

MONOCLONAL ANTI-ERK1/2 antibody produced in mouse

clone 784CT7.6.3, IgG fraction of antiserum, buffered aqueous solution

Sinónimos:

ERK1, MAPK3, Mitogen-activated protein kinase 3, PRKM3

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

784CT7.6.3, monoclonal

form

buffered aqueous solution

mol wt

43136 Da

species reactivity

mouse, human

technique(s)

western blot: 1:1000

isotype

IgG2a

UniProt accession no.

P27361,P28482

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MAPK3(5595)

Physical form

Supplied in PBS with 0.09% (W/V) sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Yuhang Yuan et al.
Cell cycle (Georgetown, Tex.), 17(11), 1390-1402 (2018-06-29)
Necrotizing enterocolitis (NEC) is a potentially fatal illness in premature neonates. Tumor necrosis factor-α (TNF-α) and autophagy are associated with the pathogenesis of NEC. This study aimed to explore whether TNF-α might regulate apoptosis in neonatal NEC model cells IEC-6
Guangchao Zhao et al.
Rejuvenation research, 22(4), 325-334 (2018-11-10)
It is known that preconditional treatment with volatile anesthetics can induce tolerance of the brain to stroke. A previous study demonstrated that the involvement of TREK-1, a two-pore domain K+ channel, in sevoflurane preconditioning induced neuroprotection against focal cerebral ischemia
Davide D'Amico et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 42(2), 462-472 (2016-08-19)
The inability to properly extinguish fear memories constitutes the foundation of several anxiety disorders, including panic disorder. Recent findings show that boosting prefrontal cortex synaptic plasticity potentiates fear extinction, suggesting that therapies that augment synaptic plasticity could prove useful in
Barathi Rajaraman et al.
Molecular and cellular biochemistry, 456(1-2), 179-190 (2019-02-16)
Hyperglycaemia during pregnancy is the main reason for developing diabetes mediated vascular complications. Advanced glycation end products (AGEs) are formed due to non-enzymatic glycation of proteins, lipids and nucleic acids during hyperglycaemia. It has the potential to damage vasculature by
Xiuli Zhang et al.
Kidney & blood pressure research, 43(2), 500-512 (2018-04-09)
Evidence from our and other groups has demonstrated that zinc transporter 7 in SLC30 family (ZnT7) inhibited epithelial-to-mesenchymal transition (EMT) and apoptosis in rat peritoneal mesothelial cells (RPMCs) under high glucose (HG) concentration. In the present study, we investigated the

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