S4819

Anti-Syntaxin 7 antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• MDL number: MFCD06798547
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 200
• conjugate: unconjugated
• antibody form: IgG fraction of antiserum
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 35 kDa
• species reactivity: rat
• technique(s): indirect immunofluorescence: 1:500-1:1000 using of rat kidney NRK cell line; western blot: 1:1000-1:2000 using whole cell extract of rat kidney NRK cell line
• UniProt accession no.: O70257
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: rat ... Stx7(60466)

Descripción

General description

Syntaxin 7 is a 35kDa protein and is a member of t-Soluble N-ethylmaleimide-sensitive factor activating protein receptor (SNARE) protein family. It is widely expressed in multiple tissues.

Immunogen

synthetic peptide corresponding to amino acids 131-149 located at the mid-region of rat syntaxin 7, conjugated to KLH. This sequence is highly conserved (two amino acid substitutions) in mouse and human syntaxin 7 (~80% identity).

Application

Anti-Syntaxin 7 antibody produced in rabbit has been used in immunoblotting and immunofluorescence.

Biochem/physiol Actions

Syntaxin 7, localized on membrane compartments of late endosomes, facilitates fusion of late endosomes with lysosomes. The protein also helps in lysosomal biogenesis. Mutant syntaxin 7 lacking the transmembrane domain blocks endocytic transport from the early to late endosome. Syntaxin 7 has been described to play an important role during phagocytosis.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable