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Merck

R3257

Sigma-Aldrich

Resorufin sodium salt

redox indicator

Sinónimos:

7-Hydroxy-3H-phenoxazin-3-one sodium salt

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About This Item

Fórmula empírica (notación de Hill):
C12H6NNaO3
Número de CAS:
Peso molecular:
235.17
Beilstein/REAXYS Number:
174850
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.28

Quality Level

form

powder

mp

>300 °C (lit.)

solubility

water: 1 mg/mL, opaque

storage temp.

room temp

SMILES string

[Na+].[O-]c1ccc2N=C3C=CC(=O)C=C3Oc2c1

InChI

1S/C12H7NO3.Na/c14-7-1-3-9-11(5-7)16-12-6-8(15)2-4-10(12)13-9;/h1-6,14H;/q;+1/p-1

InChI key

TYXBZZBYMSVFPR-UHFFFAOYSA-M

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General description

Resorufin is a fluorescent indicator.

Application

Resorufin has been used to determine the cytochrome P450 (CYP) 2A5 coumarin 7-hydroxylase (COH) activity changes over a broad range of lipopolysaccharide (LPS) doses. It has also been used as an internal standard for ethoxyresurufin-o-deethylase (EROD) analysis.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Tomas Hansson et al.
Archives of environmental contamination and toxicology, 66(2), 237-247 (2013-12-04)
Since the new millennium, a notion has developed in certain parts of society that environmental pollutants and their associated effects are under control. The primary objective of this investigation, performed in 2003, was to test whether this was actually the
L Wang et al.
Artificial cells, blood substitutes, and immobilization biotechnology, 28(3), 215-227 (2000-06-14)
Hepatocytes encapsulated in alginate-poly-1-lysine-alginate (APA) are used in transplantation studies and in bioartificial liver support systems. Loss of cell viability in the process of APA encapsulation is usually 20-30% while the effect on cytochrome CYP450 activity is rarely reported. This
2013 IEEE International Conference on Solid Dielectrics (ICSD) IEEE (2009)
Assessment of biological effects of environmental pollution in Mersin Bay (Turkey, northeastern Mediterranean Sea) using Mullus barbatus and Liza ramada as target organisms
Yilmaz D, et al.
Environmental Pollution (Barking, Essex : 1987), 208, 361-370 (2016)
Ana C A X De-Oliveira et al.
PloS one, 10(1), e0117842-e0117842 (2015-01-31)
Mouse cytochrome P450 (CYP) 2A5 is induced by inflammatory conditions and infectious diseases that down-regulate the expression and activity of most other CYP isoforms. Enhanced oxidative stress and nuclear factor (erythroid 2-related factor) 2 (Nrf2) transcription factor activation have been

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