PZ0129

CP-380736

≥98% (HPLC)

• Sinónimos: 6,7-Bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one, 6,7-Bis(2-methoxyethoxy)-4(3H)-quinazolinone, PF-00520893
• Fórmula empírica (notación de Hill): C₁₄H₁₈N₂O₅
• Número de CAS: 179688-29-0
• Peso molecular: 294.30
• MDL number: MFCD02678087
• UNSPSC Code: 51111800
• PubChem Substance ID: 329823716
• NACRES: NA.77

Propiedades

• assay: ≥98% (HPLC)
• form: powder
• color: off-white to light tan
• solubility: DMSO: ≥10 mg/mL
• storage temp.: room temp
• SMILES string: COCCOc1cc2N=CNC(=O)c2cc1OCCOC
• InChI: 1S/C14H18N2O5/c1-18-3-5-20-12-7-10-11(15-9-16-14(10)17)8-13(12)21-6-4-19-2/h7-9H,3-6H2,1-2H3,(H,15,16,17)
• InChI key: PMQWTUWLIGJTQD-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

CP-380736 is an inhibitor of the epidermal growth factor receptor (EGFR). EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important mediator of several types of cancer, including lung cancer and glioblastoma multiforme.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable