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Merck

P7786

Millipore

Protein A-Agarose from Staphylococcus aureus

aqueous suspension

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About This Item

MDL number:
UNSPSC Code:
41106500
NACRES:
NA.56

form

aqueous suspension

matrix

Cross-linked 4% beaded agarose

matrix activation

p-nitrophenyl chloroformate

matrix attachment

amino

matrix spacer

1 atom

capacity

~10 mg/mL binding capacity (human IgG)

storage temp.

2-8°C

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General description

Protein A is an immunoglobulin (Ig)-binding protein expressed in Staphylococcus aureus. It is used to purify large amounts of IgG and binds to the fraction of crystallization (Fc) part of the antibody at the CH2–CH3 interface. Protein A-agarose might be suitable for low-pressure antibody isolation. Protein A-agarose is used for affinity chromatography, antibody purification, and characterization, and protein A, G, and L-resins.

Application

Protein A-Agarose from Staphylococcus aureus has been used in immunoprecipitation. It has been used to study the effects of protein A immunoadsorption in patients with chronic dilated cardiomyopathy as well as to study multiple sclerosis and gastric cancer.

Physical form

Suspension in 0.9% NaCl containing 0.1% sodium azide

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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