P0643
5-Propyl-2-thiouracil
≥98%
Sinónimos:
PTU
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About This Item
Fórmula empírica (notación de Hill):
C7H10N2OS
Número de CAS:
Peso molecular:
170.23
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
Productos recomendados
biological source
synthetic (organic)
Quality Level
assay
≥98%
form
powder
solubility
1 M NH4OH: 50 mg/mL, clear to slightly hazy, colorless to light yellow
SMILES string
CCCC1=CNC(=S)NC1=O
InChI
1S/C7H10N2OS/c1-2-3-5-4-8-7(11)9-6(5)10/h4H,2-3H2,1H3,(H2,8,9,10,11)
InChI key
RWJRFPUNLXBCML-UHFFFAOYSA-N
Application
5-Propyl-2-thiouracil (PTU) is used to induce and study mechanisms of hypothyroidism at the levels of thyroid hormone biosynthesis and gene regulation.
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This paper describes a rapid method for confirming residues of thyreostats in meat-based baby foods by using liquid chromatography - dual polarity electrospray - tandem mass spectrometry (LC-ES(±)-MS/MS). Six thioureylenes, belonging to the group of thiouracil and imidazole, were selected
Alexander G Little et al.
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Thyroid hormone (TH) is best known for its role in development in animals, and for its control of metabolic heat production (thermogenesis) during cold acclimation in mammals. It is unknown whether the regulatory role of TH in thermogenesis is derived
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Natural products (NPs) are an attractive source of chemical diversity for small-molecule drug discovery. Several challenges nevertheless persist with respect to NP discovery, including the time and effort required for bioassay-guided isolation of bioactive NPs, and the limited biomedical relevance
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