MAK156
Fatty Acid Uptake Kit
sufficient for 100 fluorometric tests
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About This Item
EC Number:
UNSPSC Code:
12161503
Productos recomendados
usage
sufficient for 100 fluorometric tests
detection method
fluorometric
relevant disease(s)
endocrinological disorders, diabetes; gastrointestinal diseases; cancer
storage temp.
−20°C
Categorías relacionadas
General description
Fatty acids are critical for many biological processes including energy metabolism and the synthesis of structural cellular components. The facilitated uptake of fatty acids, presumably through fatty acid transport proteins, is thought to be regulated at multiple levels. The dysregulation of fatty acid uptake may contribute to diseases such as obesity, type 2 diabetes, and hepatic steatosis.
Suitability
This kit is suitable for the measurement of fatty acid uptake in cells containing fatty acid transporters
Principle
This kit is provides a simple and sensitive method for the measurement of fatty acid uptake in cells containing fatty acid transporters. This kit uses a proprietary dodecanoic acid fluorescent fatty acid substrate whose uptake into cells result in an increase in fluorescence intensity (λex = 485/λem = 515 nm).
Storage Class
10 - Combustible liquids
Certificados de análisis (COA)
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Triphenyl phosphate (TPhP) is an environmental PPARγ ligand, and growing evidence suggests that it is a metabolic disruptor. We have shown previously that the structurally similar ligand, tributyltin, does not induce brite adipocyte gene expression. Here, using in vivo and
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