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M110

Sigma-Aldrich

α-Methylserotonin maleate salt

≥98% (HPLC)

Sinónimos:

α-Methyl-5-hydroxytryptamine maleate salt, (±)-3-(2-Aminopropyl)indol-5-ol maleate salt

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About This Item

Fórmula empírica (notación de Hill):
C11H14N2O · C4H4O4
Número de CAS:
97469-12-0
Peso molecular:
306.31
MDL number:
MFCD00082468
UNSPSC Code:
12352200
PubChem Substance ID:
24278102
NACRES:
NA.77

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

H2O: >3 mg/mL, clear (warmed)

storage temp.

−20°C

SMILES string

[H]\C(=C(/[H])C(O)=O)C(O)=O.CC(N)Cc1c[nH]c2ccc(O)cc12

InChI

1S/C11H14N2O.C4H4O4/c1-7(12)4-8-6-13-11-3-2-9(14)5-10(8)11;5-3(6)1-2-4(7)8/h2-3,5-7,13-14H,4,12H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

YQNHFSXRABPJLP-BTJKTKAUSA-N

Gene Information

human ... HTR2A(3356) , HTR2B(3357) , HTR2C(3358)

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Biochem/physiol Actions

5-HT2 serotonin receptor agonist.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
104M4624V
070M4612
097K4600
122K4615
073K4617

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Ralf Buettner et al.
Molecular therapy oncolytics, 14, 149-158 (2019-06-19)
The immunosuppressive agent leflunomide has been used in the treatment of over 300,000 patients with rheumatoid arthritis. Its active metabolite, teriflunomide (Ter), directly inhibits dihydroorotate dehydrogenase (DHODH), an enzyme involved in nucleoside synthesis. We report that Ter not only shows
P D Feldman
Journal of the autonomic nervous system, 56(1-2), 119-124 (1995-12-05)
Spontaneous neuronal activity in the solitary tract nucleus was recorded extracellularly in a brain slice preparation during bath-application of 5-HT1 and 5-HT2 receptor-selective agonists and antagonists. The 5-HT1A/5-HT1B agonist 5-carboxamidotryptamine depressed activity in 20 of 25 neurons studied. The remaining
A M Ismaiel et al.
Journal of medicinal chemistry, 33(2), 755-758 (1990-02-01)
alpha-Methyl-5-hydroxytryptamine (alpha-Me-5-HT; 2) and 2-methyl-5-hydroxytryptamine (2-Me-5-HT; 3) are considered to be 5-HT2-selective and 5-HT3-selective agents, respectively. These agents were synthesized and examined at serotonin (5-HT) binding sites because there is relatively little documentation as to their selectivity and because they
G P Leung et al.
The Journal of physiology, 519 Pt 3, 657-667 (1999-08-24)
1. The short-circuit current (Isc) technique was used to study the role of 5-hydroxytryptamine (5-HT) in the regulation of anion secretion in cultured rat cauda epididymal epithelia. 2. 5-HT, the 5-HT1B-selective agonist 5-nonyloxytryptamine (5-NOT) and the 5-HT2B-selective agonist alpha-methyl-5-hydroxytryptamine (alpha-methyl-5-HT)

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