L1026

Lidocaine

analytical standard

• Sinónimos: 2-Diethylamino-N-(2,6-dimethylphenyl)acetamide, Lignocaine, Xylocaine
• Fórmula empírica (notación de Hill): C₁₄H₂₂N₂O
• Número de CAS: 137-58-6
• Peso molecular: 234.34
• EC Number: 205-302-8
• MDL number: MFCD00026733
• UNSPSC Code: 12352200
• PubChem Substance ID: 24896272
• NACRES: NA.77

Propiedades

• grade: analytical standard
• form: solid
• packaging: vial of 200 mg
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• impurities: ≤0.5% Total Organic Impurities (Lidocaine related compound H ≤0.10%; ; ; 2,6-Dimethylaniline ≤0.01%; ; ; Any unspecified impurity ≤0.10%; ; ; Total impurities ≤0.5%)
• application(s): forensics and toxicology; pharmaceutical (small molecule)
• SMILES string: CCN(CC)CC(=O)Nc1c(C)cccc1C
• InChI: 1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)
• InChI key: NNJVILVZKWQKPM-UHFFFAOYSA-N
• Gene Information: human ... CYP1A2(1544) , SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335) ; rat ... Scnn1a(25122)

Descripción

General description

Lidocaine is an amide anesthetic, which is used to treat ventricular arrhythmias. It lowers cardiac automaticity and myocardial conduction. Lidocaine inhibits the generation and conduction of nerve impulses. It has an anticonvulsant effect.

Application

Lidocaine has been used to examine its effects in inhibiting lymph flow and protection against envenomation. It has also been used to assess its efficacy as an anti-tussive agent.

Biochem/physiol Actions

Na⁺ channel blocker; class IB antiarrhythmic that is rapidly absorbed after parenteral administration.

Na⁺ channel blocker; class IB antiarrhythmic.

Packaging

Supplied in amber screw-cap vials

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves