G8171

Gambogic acid

≥95% (HPLC), powder

• Sinónimos: 1,5-Methano-1H,3H,11H-furo(3,4-g)pyrano(3,2-b)xanthene-1-crotonic acid, B"-Guttiferrin, Beta-Guttiferrin, Beta-Guttilactone, Cambogic acid, Guttatic acid, Guttic acid
• Fórmula empírica (notación de Hill): C₃₈H₄₄O₈
• Número de CAS: 2752-65-0
• Peso molecular: 628.75
• UNSPSC Code: 12352200
• PubChem Substance ID: 329799975

Propiedades

• Quality Level: 100
• assay: ≥95% (HPLC)
• form: powder
• color: yellow to orange
• solubility: DMSO: ≥10 mg/mL; H₂O: insoluble
• storage temp.: −20°C
• SMILES string: C\C(C)=C\CC[C@@]1(C)Oc2c(C\C=C(\C)C)c3O[C@@]45[C@@H]6C[C@@H](C=C4C(=O)c3c(O)c2C=C1)C(=O)[C@]5(C\C=C(\C)C(O)=O)OC6(C)C
• InChI: 1S/C38H44O8/c1-20(2)10-9-15-36(8)16-14-24-29(39)28-30(40)26-18-23-19-27-35(6,7)46-37(33(23)41,17-13-22(5)34(42)43)38(26,27)45-32(28)25(31(24)44-36)12-11-21(3)4/h10-11,13-14,16,18,23,27,39H,9,12,15,17,19H2,1-8H3,(H,42,43)/b22-13-/t23-,27+,36-,37+,38-/m1/s1
• InChI key: GEZHEQNLKAOMCA-RRZNCOCZSA-N

Descripción

Biochem/physiol Actions

Gambogic acid acts as a caspase activator and apoptosis inducer, which causes an irreversible arrest in the G2/M phase of the cell cycle.

Features and Benefits

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.