G3002
Gly-Pro
≥98%, suitable for ligand binding assays
Sinónimos:
glycyl-L-proline
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About This Item
Productos recomendados
Nombre del producto
Gly-Pro,
assay
≥98%
Quality Level
form
solid
technique(s)
ligand binding assay: suitable
color
white
storage temp.
−20°C
SMILES string
NCC(N1[C@H](C(O)=O)CCC1)=O
InChI
1S/C7H12N2O3/c8-4-6(10)9-3-1-2-5(9)7(11)12/h5H,1-4,8H2,(H,11,12)
InChI key
KZNQNBZMBZJQJO-UHFFFAOYSA-N
Application
- Diagnostic efficacy of [(68)Ga]Ga-DOTA-GPFAPI-04 in patients with solid tumors in a head-to-head comparison with [(18)F]F-FDG: results from a prospective clinical study.: This study explores the use of Gly-Pro in peptide imaging agents, specifically [(68)Ga]Ga-DOTA-GPFAPI-04, demonstrating its superior diagnostic performance in detecting solid tumors compared to traditional imaging modalities, offering new avenues for cancer diagnosis and monitoring (Yuan et al., 2024).
- Understanding the Transepithelial Transport and Transbilayer Diffusion of the Antihypertensive Peptide Asn-Cys-Trp: Insights from Caco-2 Cell Monolayers and the DPPC Model Membrane.: This research demonstrates the utility of Gly-Pro in studying the absorption and metabolic stability of antihypertensive peptides, providing key insights into their pharmacokinetic behaviors and enhancing drug delivery strategies (Wu et al., 2024).
signalword
Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Faraday discussions, 204, 69-81 (2017-08-03)
Adsorption of the Glycine-Proline (Gly-Pro) dipeptide has been investigated using surface science complementary techniques on Au(110) and Ag(110), showing some interesting differences both in the chemical form and surface organization of the adsorbed peptide. On Au(110), Gly-Pro mainly adsorbs in
Mitsuru Tanaka et al.
Scientific reports, 9(1), 5769-5769 (2019-04-10)
Apart from nutrients required for the brain, there has been no report that naturally occurring peptides can cross the blood-brain barrier (BBB). The aim of this study was to identify the BBB-transportable peptides using in situ mouse perfusion experiments. Based
E Berardesca et al.
The British journal of dermatology, 126(2), 193-195 (1992-02-01)
A case is reported of a 15-year-old boy with prolidase deficiency and marked urinary excretion of the iminodipeptide gly-pro. Prolidase activity of erythrocytes against substrate glycyl-proline was deficient, but after blood transfusions this was increased to 15.7% of donor activity
Binah Baht Ysrayl et al.
Scientific reports, 9(1), 2567-2567 (2019-02-24)
Cocaine use is associated with breach in the blood brain barrier (BBB) and increased HIV-1 neuro-invasion. We show that the cellular enzyme "Prolidase" plays a key role in cocaine-induced disruption of the BBB. We established a barrier model to mimic
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