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Merck

G1149

Sigma-Aldrich

L-Glutamic acid potassium salt monohydrate

BioReagent, suitable for insect cell culture, ≥99% (HPLC)

Sinónimos:

(S)-2-Aminopentanedioic acid, L-α-Aminoglutaric acid potassium salt, L-2-Aminopentanedioic acid potassium salt, Glu, Potassium L-glutamate

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About This Item

Fórmula empírica (notación de Hill):
C5H8KNO4 · H2O
Número de CAS:
Peso molecular:
203.23
Beilstein/REAXYS Number:
3637377
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.75

product line

BioReagent

assay

≥99% (HPLC)

form

powder

technique(s)

cell culture | insect: suitable

color

white

SMILES string

O.[K+].N[C@@H](CCC([O-])=O)C(O)=O

InChI

1S/C5H9NO4.K.H2O/c6-3(5(9)10)1-2-4(7)8;;/h3H,1-2,6H2,(H,7,8)(H,9,10);;1H2/q;+1;/p-1/t3-;;/m0../s1

InChI key

XIBUKSQTWSKJMQ-QTNFYWBSSA-M

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General description

L-Glutamic acid, an amino acid is mainly found in various food products in its free form. It is ubiquitously present in the brain of mammals.

Application

L-Glutamic acid potassium salt monohydrate has been used as a component in KG buffer for cardiomyocyte isolation and culture.

Biochem/physiol Actions

L-Glutamic acid plays a major role in several metabolic pathways. It acts as excitatory neurotransmitter in the cerebral cortex. An plays a key role in learning, memory and brain aging processes. It is involved in neuronal differentiation, migration and survival in the developing brain. High levels of glutamic acid is observed in Alzheimer′s, Parkinson′s diseases and epilepsy.
Agonist at kainate, NMDA, and quisqualate receptors; an excitatory amino acid neurotransmitter.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Stability and solution structure of binary and ternary Cu (II) complexes with l-glutamic acid and diamines as well as adducts in metal-free systems in aqueous solution
Bregier-JR
Journal of Solution Chemistry, 43(12), 2144-2162 (2014)
The HCM-linked W792R mutation in cardiac myosin-binding protein C reduces C6 FnIII domain stability
Smelter DF, et al.
American Journal of Physiology. Heart and Circulatory Physiology, 314(6), H1179-H1191 (2018)
Eric A Josephs et al.
DNA repair, 35, 71-84 (2015-10-16)
In Escherichia coli, errors in newly-replicated DNA, such as the incorporation of a nucleotide with a mis-paired base or an accidental insertion or deletion of nucleotides, are corrected by a methyl-directed mismatch repair (MMR) pathway. While the enzymology of MMR
Oksana Forostyak et al.
Stem cells and development, 22(10), 1506-1521 (2013-01-09)
Human embryonic stem cell-derived neural precursors (hESC NPs) are considered to be a promising tool for cell-based therapy in central nervous system injuries and neurodegenerative diseases. The Ca(2+) ion is an important intracellular messenger essential for the regulation of various

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