F3388

Ferric citrate

BioReagent, suitable for cell culture

• Sinónimos: Iron(III) citrate, Iron(III) citrate hydrate
• Fórmula empírica (notación de Hill): C₆H₅FeO₇
• Número de CAS: 3522-50-7
• Peso molecular: 244.94
• EC Number: 222-536-6
• MDL number: MFCD00013098
• UNSPSC Code: 12352205
• PubChem Substance ID: 24894843
• NACRES: NA.75

Propiedades

• biological source: synthetic (organic)
• product line: BioReagent
• technique(s): cell culture | mammalian: suitable
• solubility: hot water: 0.01 g/mL, clear, orange-yellow
• shipped in: ambient
• storage temp.: room temp
• SMILES string: OC12CC(=O)O[Fe](OC(=O)C1)OC2=O
• InChI: 1S/C6H8O7.Fe/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);/q;+3/p-3
• InChI key: NPFOYSMITVOQOS-UHFFFAOYSA-K

Descripción

Application

Ferric citrate provides a source of iron used in cell culture applications. It provides iron in a less toxic form than free iron salts. Ferric citrate has been used as medium supplement in human osteosarcoma cell (U2OS) culture, human embryonic kidney (HEK293) cells and adult primary cardiomyocytes.

Biochem/physiol Actions

Ferric citrate is used as a component of protein-free medium. It is used as a substitute for transferrin in mouse hybridomas culture. Ferric citrate enhances IgM production. It indirectly stimulates the mitogen-activated protein kinase (MAPK) by favoring high amphiregulin oncoprotein levels in colon cancer.  Ferric citrate is effective in binding to phosphate in patients with dialysis-dependent chronic kidney disease.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)