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Key Documents

D9321

Sigma-Aldrich

D-dimer, Human

from human plasma, buffered aqueous solution

Sinónimos:

Fibrin degradation fragment, Fragment D-dimer

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About This Item

UNSPSC Code:
12352204
NACRES:
NA.61

biological source

human plasma

form

buffered aqueous solution

mol wt

Mw ~200 kDa

shipped in

wet ice

storage temp.

−20°C

General description

The human D-dimer(s) protein is an indicator of a thrombosis event. This protein is the degradation fragment of fibrin mesh that has been stabilized by Factor XIII. This factor crosslinks the E-element to two D-elements. As a result, this crosslink is the final step in the generation of a thrombus.

Application

The human D-dimer protein is a blood test performed in the medical laboratory to diagnose thrombosis. While a negative human D-dimer result rules out thrombosis, a positive test result can indicate thrombosis or other underlying potential health problems. The presence of D-dimer can idicate the existance of a deep venous thrombosis (DVT) or pulomonary embolism (PE).

Physical form

The human D-dimer protein provided in liquid form constisting of 0.05 M sodium phosphate, pH 7.5, 0.15 M sodium chloride and 0.09% sodium azide.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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