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D8399

Sigma-Aldrich

Danazol

≥98% (TLC), powder, androgen receptor agonist

Sinónimos:

17β-Hydroxy-2,4,17α-pregnadien-20-yno[2,3-d]isoxazole, 2,4,17α-Pregnadien-20-yno[2,3-d]­isoxa­zol-17-ol

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About This Item

Fórmula empírica (notación de Hill):
C22H27NO2
Número de CAS:
17230-88-5
Peso molecular:
337.46
EC Number:
241-270-1
MDL number:
MFCD00056838
UNSPSC Code:
51111800
PubChem Substance ID:
24277708
NACRES:
NA.77

product name

Danazol, ≥98%

Quality Level

200

assay

≥98%

form

powder

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

originator

Sanofi Aventis

SMILES string

CC12Cc3cnoc3C=C1CCC4C2CCC5(C)C4CC[C@@]5(O)C#C

InChI

1S/C22H27NO2/c1-4-22(24)10-8-18-16-6-5-15-11-19-14(13-23-25-19)12-20(15,2)17(16)7-9-21(18,22)3/h1,11,13,16-18,24H,5-10,12H2,2-3H3/t16?,17?,18?,20?,21?,22-/m0/s1

InChI key

POZRVZJJTULAOH-ZIKCMSSPSA-N

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Biochem/physiol Actions

Danazol is a weak androgen; anterior pituitary suppressant.

Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Repr. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Maria Vertzoni et al.
Molecular pharmaceutics, 9(5), 1189-1198 (2012-04-10)
The first aim of this study was to characterize the luminal contents and their micellar phase after the administration of a heterogeneous liquid meal to healthy adults. The second aim was to evaluate the impact of micellar lipids and coarse
Gregory W Thomas et al.
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Breakdown of endothelial barrier function is a hallmark event across a variety of pathologies such as inflammation, cancer, and diabetes. It has also been appreciated that steroid hormones impart direct biological activity on endothelial cells at many levels. The purpose
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