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D0776

Sigma-Aldrich

2′-Deoxycytidine hydrochloride

BioReagent, suitable for cell culture

Sinónimos:

1-(2-Deoxy-β-D-ribofuranosyl)cytosine hydrochloride, Cytosine deoxyriboside hydrochloride

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About This Item

Fórmula empírica (notación de Hill):
C9H13N3O4 · HCl
Número de CAS:
3992-42-5
Peso molecular:
263.68
Beilstein/REAXYS Number:
3576124
EC Number:
223-639-9
MDL number:
MFCD00012840
UNSPSC Code:
12352207
PubChem Substance ID:
24893295
NACRES:
NA.75

biological source

synthetic

product line

BioReagent

assay

≥99% (HPLC)

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

water: 50 mg/mL, clear, colorless

SMILES string

Cl[H].NC1=NC(=O)N(C=C1)[C@H]2C[C@H](O)[C@@H](CO)O2

InChI

1S/C9H13N3O4.ClH/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8;/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15);1H/t5-,6+,8+;/m0./s1

InChI key

LTKCXZGFJFAPLY-OERIEOFYSA-N

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Application

2′-Deoxycytidine hydrochloride has been used:
  • as a deoxyribonucleoside component in the basal medium to study its effects on Bacillus mojavensis′s anaerobic growth
  • in the infectivity assay of monocyte-derived macrophages by human immunodeficiency virus 1 (HIV-1)
  • in nucleoside supplementation for the synchronization of human retinal pigment epithelial-1 (RPE-1) cells in G1 phase

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Sigma-Aldrich

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Sigma-Aldrich

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Sigma-Aldrich

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Timidina ≥99.0% (HPLC)

Sigma-Aldrich

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Timidina

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The Ras family G-proteins RalA and RalB make critical non-overlapping contributions to the generation of a tumorigenic regulatory network, supporting bypass of the normal restraints on both cell proliferation and survival. The Sec6/8 complex, or exocyst, has emerged as a
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Template switching between two distinct HIV-1 RNA genomes during reverse transcription gives rise to recombinant viruses that greatly expand the genetic diversity of HIV-1 and have adverse implications for drug resistance, immune escape, and vaccine design. Virions with two distinct
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Oncotarget, 6(14), 12697-12709 (2015-04-18)
CCDC6 gene product is a pro-apoptotic protein substrate of ATM, whose loss or inactivation enhances tumour progression. In primary tumours, the impaired function of CCDC6 protein has been ascribed to CCDC6 rearrangements and to somatic mutations in several neoplasia. Recently

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