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C4361

Sigma-Aldrich

Collagen Type I−FITC Conjugate from bovine skin

~1 mg/mL, solution

Sinónimos:

Collagen from bovine skin

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About This Item

Número de CAS:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.32

biological source

bovine skin

Quality Level

form

solution

availability

not available in Canada (at this time; for questions or status updates, please email us at antibody.canada@sial.com)

concentration

~1 mg/mL

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

General description

Type I collagen is the major collagen of tendon and bone, but it is widely distributed in other tissues, such as skin, cornea, tooth dentin, heart valve, lung, liver, fascia and scar tissue.

Application

Collagen Type I-FITC Conjugate from bovine skin has been used in collagen I gel deformation analysis. It has also been used to coat silicone elastic membranes for seeding cells for various experimental studies. It can also be used as a substrate for assaying mammalian collagenase activity in cell culture.

Biochem/physiol Actions

Collagen type I offers mechanical stability, strength and toughness to a range of tissues from tendons and ligaments, to skin, cornea, bone and dentin.

Physical form

Supplied in 0.01 M acetic acid.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Faceshields, Gloves, Goggles


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There is evidence to suggest that the synthesis of type II collagen is increased in osteoarthritis (OA). Using an immunoassay, we show that the content of the C-propeptide of type II procollagen (CPII), released extracellularly from the newly synthesized molecule

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