C3635
4-Chloro-DL-phenylalanine methyl ester hydrochloride
Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
About This Item
Fórmula lineal:
ClC6H4CH2CH(NH2)CO2CH3·HCl
Número de CAS:
Peso molecular:
250.12
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.32
Productos recomendados
form
powder
Quality Level
mp
186-189 °C (lit.)
storage temp.
−20°C
SMILES string
Cl.COC(=O)C(N)Cc1ccc(Cl)cc1
InChI
1S/C10H12ClNO2.ClH/c1-14-10(13)9(12)6-7-2-4-8(11)5-3-7;/h2-5,9H,6,12H2,1H3;1H
InChI key
GCBCWTWQAFLKJG-UHFFFAOYSA-N
Gene Information
human ... TPH1(7166) , TPH2(121278)
¿Está buscando productos similares? Visita Guía de comparación de productos
General description
4-Chloro-DL-phenylalanine methyl ester hydrochloride stimulates glucose intolerance in pregnant mice. Studies have shown that 4-Chloro-DL-phenylalanine methyl ester hydrochloride is associated with cognitive defects in rodents.
Application
4-Chloro-DL-phenylalanine methyl ester hydrochloride has been used to induce 5-hydroxytryptamine (5-HT) depletion in rats.
Biochem/physiol Actions
Tryptophan hydroxylase inhibitor. Crosses blood brain barrier better than p−chlorophenylalanine.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Elija entre una de las versiones más recientes:
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Jessica E Monk et al.
Frontiers in behavioral neuroscience, 12, 246-246 (2018-11-09)
Negative affective states such as anxiety and depression pose a risk to animal welfare, however, practical tests for assessing these states in animals are limited. In humans, anxious individuals are shown to pay more attention toward threatening information than non-anxious
Serotonin regulates pancreatic beta cell mass during pregnancy
Kim H, et al.
Nature Medicine, 16(7), 804-804 (2010)
Serotonin depletion results in a decrease of the neuronal activation caused by rivastigmine in the rat hippocampus
Kornum BR, et al.
Brain Research, 1073, 262-268 (2006)
Vortioxetine dose-dependently reverses 5-HT depletion-induced deficits in spatial working and object recognition memory: a potential role for 5-HT1A receptor agonism and 5-HT3 receptor antagonism
du Jardin KG, et al.
European Neuropsychopharmacology, 24(1), 160-171 (2014)
F Denk et al.
Psychopharmacology, 179(3), 587-596 (2005-05-03)
Although tasks assessing the role of dopamine in effort-reward decisions are similar to those concerned with the role of serotonin in impulsive choice in that both require analysis of the costs and benefits of possible actions, they have never been
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico