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Merck

A8511

Sigma-Aldrich

Luminol

≥97% (HPLC)

Sinónimos:

3-Aminophthalhydrazide, 5-Amino-2,3-dihydro-1,4-phthalazinedione

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About This Item

Fórmula empírica (notación de Hill):
C8H7N3O2
Número de CAS:
Peso molecular:
177.16
Beilstein/REAXYS Number:
383929
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.83

Quality Level

assay

≥97% (HPLC)

form

powder or chunks

mp

>300 °C (lit.)

solubility

DMSO: 50 mg/mL, clear to slightly hazy

SMILES string

Nc1cccc2C(=O)NNC(=O)c12

InChI

1S/C8H7N3O2/c9-5-3-1-2-4-6(5)8(13)11-10-7(4)12/h1-3H,9H2,(H,10,12)(H,11,13)

InChI key

HWYHZTIRURJOHG-UHFFFAOYSA-N

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General description

Luminol is a chemiluminescent compound, which belongs to the class of cyclic acyl hydrazides. It exhibits chemiluminescence, when oxidized by oxidizing agents. Luminol may be associated with nausea, vomiting and mucosa irritation in eyes and skin.

Application

Luminol has been used in chemiluminescence assay.

Features and Benefits

Used for chemiluminescence analysis of, for example, metal cations, blood, and glucococorticoids.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificados de análisis (COA)

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Agarwal A, et al.
Journal of Assisted Reproduction and Genetics, 32(12), 1721-1729 (2015)
Luminol-based chemiluminescent signals: clinical and non-clinical application and future uses
Khan P, et al.
Applied Biochemistry and Biotechnology, 173(2), 333-355 (2014)
Christophe A Marquette et al.
Analytical and bioanalytical chemistry, 385(3), 546-554 (2006-05-23)
This critical review discusses the results published between 2000 and 2005 on the development of analytical systems based on the luminol chemiluminescent and electrochemiluminescent reactions. An increasing number of non-specific detection systems based on the enhancing, inhibiting or catalysing effect
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The Cu(2+)-dependent ligation DNAzyme is implemented as a biocatalyst for the colorimetric or chemiluminescence detection of Cu(2+) ions, Hg(2+) ions, or cocaine. These sensing platforms are based on the structural tailoring of the sequence of the Cu(2+)-dependent ligation DNAzyme for
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Esophageal cancer patients with pathological complete response (pCR) to neoadjuvant chemoradiation (CRT) have favorable outcomes. Currently, there was no reliable biomarker predicting the response to CRT. Perioperative circulating mRNA may be associated with prognosis, but its application for predicting treatment

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