A6608
Albúmina human
recombinant, expressed in Saccharomyces cerevisiae, aqueous solution, 10% in aqueous buffer, ≥99% (agarose gel electrophoresis)
Sinónimos:
rHSA
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About This Item
Fórmula empírica (notación de Hill):
C2936H4624N786O889S41
Número de CAS:
Peso molecular:
66471.53
MDL number:
UNSPSC Code:
12352202
eCl@ss:
42010201
NACRES:
NA.25
Productos recomendados
biological source
human
Quality Level
recombinant
expressed in Saccharomyces cerevisiae
assay
≥99% (agarose gel electrophoresis)
form
aqueous solution
mol wt
monomer ~67 kDa
concentration
10% in aqueous buffer
technique(s)
cell culture | mammalian: suitable
UniProt accession no.
storage temp.
2-8°C
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
InChI key
QYSGYZVSCZSLHT-UHFFFAOYSA-N
Gene Information
human ... ALB(213)
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General description
Albumin constitutes 25% of the proteins produced by the liver and is a prominent protein found in the blood. It is a protein of a single polypeptide chain with a thiol group.
Application
Esta variante recombinante se recomienda para investigación en absorción, distribución, metabolismo y excreción (ADME) farmacológica; cultivo celular; investigación de administración de medicamentos; y crioconservación de las células.
Albumin human has been used:
- to study its adsorption process on model mica surface at pH 3.5 using the atomic force microscopy (AFM) and in situ streaming potential measurements
- to study its proteolytic activities under reducing conditions
- in the medium for stem cell cultivation
Biochem/physiol Actions
Albumin is a binding and transport protein that serves as a protein repository and a carrier for amino acids. Albumin binding dissolves the biomolecules in blood and ensures its effective transport. This also prevents the loss of substance through excretion. Pathological conditions like vasculitis, lymphangiectasia, glomerulonephritis, and hepatic sinusoidal hypertension might result in hypoalbuminemia. This product can be used in the pharmaceutical industry as a drug excipient and to coat medical devices.
Las albúminas son proteínas monómeras solubles que se encuentran en los líquidos y los tejidos de los animales y en algunas semillas vegetales. La seroalbúmina funciona como proteína transportadora para esteroides, ácidos grasos y hormonas tiroideas. Las seroalbúminas son también vitales en la regulación de las presiones osmóticas coloidales de la sangre.
Analysis Note
Endotoxin tested
Other Notes
Encontrará más información en seroalbúmina humana.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificados de análisis (COA)
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N A Pham et al.
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Protein carbonylation is an irreversible modification of Lys, Arg, Thr and Pro amino acids under conditions of oxidative stress. Previous studies have reported specific carbonylated residues in purified recombinant albumins, albeit with a lack of agreement between the studies. Currently
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