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Merck

Y0000836

Nifuroxazide

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

5-Nitro-2-furaldehyde p-hydroxybenzoylhydrazone

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About This Item

Fórmula empírica (notación de Hill):
C12H9N3O5
Número de CAS:
Peso molecular:
275.22
Beilstein/REAXYS Number:
4264976
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

nifuroxazide

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Oc1ccc(cc1)C(=O)N\N=C\c2ccc(o2)[N+]([O-])=O

InChI

1S/C12H9N3O5/c16-9-3-1-8(2-4-9)12(17)14-13-7-10-5-6-11(20-10)15(18)19/h1-7,16H,(H,14,17)/b13-7+

InChI key

YCWSUKQGVSGXJO-NTUHNPAUSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Nifuroxazide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Determination of nifuroxazide in biological fluid by automated high-performance liquid chromatography with large-volume injection.
Guinebault R P, et al.
Journal of Chromatography A, 204, 329-333 (1981)
Maurice Hofnung et al.
Research in microbiology, 153(7), 427-434 (2002-10-31)
Two nitrofurans present broad-spectrum antimicrobial properties and some of them are used in human and veterinary medicine. Most of these molecules are mutagens and some of them were reported as carcinogens. Due to its extreme mutagenic potency in bacteria, the
S R Walker et al.
Oncogene, 34(9), 1073-1082 (2014-03-26)
Inappropriate expression or activation of transcription factors can drive patterns of gene expression, leading to the malignant behavior of breast cancer cells. We have found that the transcriptional repressor BCL6 is highly expressed in breast cancer cell lines, and its
A Kaufmann et al.
Analytica chimica acta, 862, 41-52 (2015-02-16)
An ultra-high performance liquid chromatography based method, coupled to high resolution mass spectrometry (UHPLC-HRMS), was developed to permit the detection and quantification of various nitrofuran and chloramphenicol residues in a number of animal based food products. This method is based

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