PHR1319

Trichloroethylene

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: Trichloroethylene, TCE, Trichloroethene
• Fórmula lineal: ClCH=CCl₂
• Número de CAS: 79-01-6
• Peso molecular: 131.39
• Beilstein/REAXYS Number: 1736782
• MDL number: MFCD00000838
• UNSPSC Code: 41116107
• PubChem Substance ID: 329823304

Propiedades

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to USP 1601827
• vapor density: 4.5 (vs air)
• vapor pressure: 61 mmHg ( 20 °C)
• CofA: current certificate can be downloaded
• autoignition temp.: 770 °F
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• refractive index: n20/D 1.476 (lit.)
• bp: 86.7 °C (lit.)
• mp: −84.8 °C (lit.)
• density: 1.463 g/mL at 25 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: single component solution
• storage temp.: 2-30°C
• SMILES string: Cl\C=C(\Cl)Cl
• InChI: 1S/C2HCl3/c3-1-2(4)5/h1H
• InChI key: XSTXAVWGXDQKEL-UHFFFAOYSA-N

Descripción

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Residual Solvent - Trichloroethylene belongs to the group of class 2 residual solvents. The use of class 2 solvents should be limited in drug substances, excipients, dietary ingredients, and official products because of the inherent toxicities of these residual solvents. Trichloroethylene is a volatile and chlorinated organic compound, which finds applications as a solvent and greasing agent.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA0678 in the slot below. This is an example certificate only and may not be the lot that you receive.

Información de seguridad

• pictograms: GHS08
• signalword: Danger
• hcodes: H350
• pcodes: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Carc. 1B
• Storage Class: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: 188.6 °F - closed cup
• flash_point_c: 87 °C - closed cup