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Key Documents

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I0627

Supelco

Isobarbituric acid

analytical standard

Sinónimos:

2,4,5-Trihydroxypyrimidine, 5-Hydroxyuracil

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About This Item

Fórmula empírica (notación de Hill):
C4H4N2O3
Número de CAS:
496-76-4
Peso molecular:
128.09
Beilstein/REAXYS Number:
127205
EC Number:
207-829-9
MDL number:
MFCD00082987
UNSPSC Code:
41116107
PubChem Substance ID:
329815320
NACRES:
NA.24

grade

analytical standard

Quality Level

100

assay

~98%

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

>300 °C (dec.) (lit.)

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

O=C1CNC(=O)NC1=O

InChI

1S/C4H4N2O3/c7-2-1-5-4(9)6-3(2)8/h1H2,(H2,5,6,8,9)

InChI key

FQXOOGHQVPKHPG-UHFFFAOYSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
STBK5580
STBJ8650
STBH7050
STBG9194
STBF8677V

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Grégory Eot-Houllier et al.
Nucleic acids research, 35(10), 3355-3366 (2007-05-01)
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Zuzanna Bukowy et al.
Nucleic acids research, 36(15), 4975-4987 (2008-07-29)
Werner syndrome (WS) is a premature aging disorder caused by mutations in the WS gene (WRN). Although WRN has been suggested to play an important role in DNA metabolic pathways, such as recombination, replication and repair, its precise role still
Jason L Parsons et al.
Nucleic acids research, 33(15), 4849-4856 (2005-09-01)
Base excision repair is the major pathway for the repair of oxidative DNA damage in human cells that is initiated by a damage-specific DNA glycosylase. In human cells, the major DNA glycosylases for the excision of oxidative base damage are
Grégory Eot-Houllier et al.
Nucleic acids research, 33(1), 260-271 (2005-01-14)
Clustered DNA lesions, possibly induced by ionizing radiation, constitute a trial for repair processes. Indeed, recent studies suggest that repair of such lesions may be compromised, potentially leading to the formation of lethal double-strand breaks (DSBs). A complex multiply damaged
Gunn A Hildrestrand et al.
Experimental cell research, 315(15), 2558-2567 (2009-05-30)
Adipose-tissue derived mesenchymal stem cells (AT-MSCs) are a promising tool for use in cell-based therapies. However, in vitro expansion is required to obtain clinically relevant cell numbers, and this might increase the chance of genomic instability. DNA repair is crucial
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