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G1522

Sigma-Aldrich

Gentamicin

solution, suitable for hybridoma, BioReagent

Sinónimos:

Garamycin, Gentiomycin C

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About This Item

Número de CAS:
1405-41-0
MDL number:
MFCD00270181
UNSPSC Code:
12352207
eCl@ss:
42020823
PubChem Substance ID:
329799845
NACRES:
NA.76

product name

Gentamicina solution, Hybri-Max™, 0.1 μm filtered, 50 mg/mL gentamicin, BioReagent, suitable for hybridoma

grade

Hybri-Max™

Quality Level

300

sterility

0.1 μm filtered

product line

BioReagent

form

liquid

quality

Prepared in tissue culture grade water.

concentration

50 mg/mL gentamicin

technique(s)

cell culture | hybridoma: suitable

impurities

endotoxin, tested

color

colorless to light yellow

density

1.000 g/cm3

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria
mycoplasma

mode of action

protein synthesis | interferes

storage temp.

2-8°C

SMILES string

OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@H](OC[C@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](CN)CC[C@H]3N)[C@@H]2O.CN[C@@H]4[C@@H](O)[C@H](OC[C@]4(C)O)O[C@H]5[C@H](N)C[C@H](N)[C@@H](O[C@H]6O[C@@H](CC[C@H]6N)[C@@H](C)N)[C@@H]5O.CN[C@H](C)[C@@H]7CC[C@@H](N)[C@H](O7)O[C@@H]8[C@@H](N)C[C@@H](N)[C@H](O[C@H]9OC[C@](C)(O)[C@H](NC)[C@H]9O)[C@H]8O

InChI

1S/C21H43N5O7.C20H41N5O7.C19H39N5O7.H2O4S/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20;1-8(21)12-5-4-9(22)18(30-12)31-15-10(23)6-11(24)16(13(15)26)32-19-14(27)17(25-3)20(2,28)7-29-19;1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;1-5(2,3)4/h9-20,25-29H,5-8,22-24H2,1-4H3;8-19,25-28H,4-7,21-24H2,1-3H3;8-18,24-27H,3-7,20-23H2,1-2H3;(H2,1,2,3,4)/t9-,10-,11+,12-,13+,14+,15-,16-,17+,18-,19-,20-,21+;8-,9-,10+,11-,12+,13+,14-,15-,16+,17-,18-,19-,20+;8-,9+,10-,11+,12-,13+,14+,15-,16+,17+,18+,19-;/m110./s1

InChI key

RDEIXVOBVLKYNT-HDZPSJEVSA-N

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General description

Chemical structure: aminoglycoside

Application

Gentamicin solution has been used to study its dose-related antipruritic effects on serotonin (5-HT)-induced scratching model. It has also been used in electrophysiological analysis.

Biochem/physiol Actions

Modo de acción: La gentamicina inhibe la síntesis de proteínas uniéndose a la subunidad 30S del ribosoma.

Espectro antimicrobiano: Incluye bacterias gramnegativas y grampositivas, entre ellas cepas resistentes a la tetraciclina, el cloranfenicol, la canamicina y la colistina, en particular cepas de pseudomonas, Proteus, Staphylococcus y Streptococcus.

Components

Gentamicin is an aminoglycoside complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is used as the sulfate salt. There are three components, each consisting of five basic nitrogens and requiresing five equivalents of sulfuric acid per mole of gentamicin base.

Caution

The product is stable at 37° for 5 days and is stored at 2-8°C.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Replaced by

Referencia del producto
Descripción
Precios

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
058M4897V
037M4840V
076M4858V
035M4802V
094M4798V

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