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Key Documents

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C2510000

Codergocrine mesilate

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

Ergoloid mesylate salt, Dihydroergotoxin mesylate salt

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About This Item

Número de CAS:
8067-24-1
MDL number:
MFCD00209881
UNSPSC Code:
41116107
PubChem Substance ID:
329775009
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

codergocrine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CS(O)(=O)=O.CC(CO)NC(=O)C1CC2C(Cc3c[nH]c4cccc2c34)N(C)C1

InChI

1S/C19H25N3O2.CH4O3S/c1-11(10-23)21-19(24)13-6-15-14-4-3-5-16-18(14)12(8-20-16)7-17(15)22(2)9-13;1-5(2,3)4/h3-5,8,11,13,15,17,20,23H,6-7,9-10H2,1-2H3,(H,21,24);1H3,(H,2,3,4)

InChI key

ONYMVHQTXOEAOV-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Codergocrine mesilate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Certificados de análisis (COA)

Lot/Batch Number

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Chaoqun Yu et al.
International journal of pharmaceutics, 375(1-2), 16-21 (2009-06-09)
The aim of this investigation was to prepare ergoloid mesylate submicron emulsions (EMSEs) for enhancing nasal absorption of drug and reducing nasal ciliotoxicity. Following intranasal administrations of EMSE and ergoloid mesylate solution (EMS) and intravenous administration of EMS to rats
Drugs to treat Alzheimer's disease.
Journal of psychosocial nursing and mental health services, 47(4), 13-14 (2009-05-15)
E V Iarnykh et al.
Terapevticheskii arkhiv, 72(11), 47-50 (2001-03-29)
To assess a hypotensive effect of redergin (dihydroergotoxin)--agonist of dopaminergic receptors--in monotherapy (4.5-6 mg/day) and in combination with enalapril and amlodipin (10 mg/day). Redergin in monotherapy or combined therapy was given to 106 hypertensive women in pre- or postmenopause and
J Olin et al.
The Cochrane database of systematic reviews, (2)(2), CD000359-CD000359 (2000-05-05)
Currently hydergine is used almost exclusively for treating patients with either dementia, or 'age-related' cognitive symptoms. Since the early eighties there have been over a dozen more clinical trials, yet hydergine's efficacy remains uncertain. Although previous reviews offer generally favorable
[Can a hydergine therapy lead to damage of the coronary vessels?].
Frank Ulrich Müller
Deutsche medizinische Wochenschrift (1946), 127(25-26), 1401-1401 (2002-07-24)
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