Saltar al contenido
Merck
Todas las fotos(1)

Documentos

62484

Sigma-Aldrich

Lithium citrate tribasic tetrahydrate

BioUltra, ≥99.5% (NT)

Sinónimos:

Citric acid trilithium salt, Trilithium citrate tetrahydrate

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula lineal:
HOC(COOLi)(CH2COOLi)2 · 4H2O
Número de CAS:
6080-58-6
Peso molecular:
281.98
EC Number:
213-045-8
MDL number:
MFCD00150030
UNSPSC Code:
12161700
PubChem Substance ID:
329759732
NACRES:
NA.25

product line

BioUltra

Quality Level

200

assay

≥99.5% (NT)

form

solid

impurities

insoluble matter, passes filter test

pH

8.0-9.5 (25 °C, 1 M in H2O)

solubility

H2O: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

1 M in H2O

UV absorption

λ: 260 nm Amax: 0.040
λ: 280 nm Amax: 0.016

SMILES string

[Li+].[Li+].[Li+].O.O.O.O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

InChI

1S/C6H8O7.3Li.4H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;4*1H2/q;3*+1;;;;/p-3

InChI key

HXGWMCJZLNWEBC-UHFFFAOYSA-K

Gene Information

human ... GSK3A(2931) , GSK3B(2932) , IMPA1(3612)

¿Está buscando productos similares? Visita Guía de comparación de productos

Application

Lithium citrate is useful as a potential therapeutic for Canavan disease due to aspartoacylase deficiency or aminoacylase 2 deficiency.

Other Notes

Quantification of physiological amino acids by gradient lithium ion-exchange HPLC

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificados de análisis (COA)

Lot/Batch Number
BCCH1073
BCCC9061
BCBZ4546
BCBV6100
BCBT6543

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

S E Møller
Journal of chromatography, 613(2), 223-230 (1993-04-02)
A single-column gradient lithium ion-exchange chromatographic method with post-column derivatization and fluorimetric detection for the quantification of physiological amino acids is described. The method runs automatically, requires a minimum of sample preparation, separates all amino acids in plasma and cerebrospinal
Lithium citrate reduces excessive intra-cerebral N-acetyl aspartate in Canavan disease.
Assadi M, Janson C, Wang DJ, et al.
European Journal of Pediatrics, 14, 354-359 (2010)
María Dolores Edo Solsona et al.
Clinical neuropharmacology, 35(3), 150-151 (2012-05-18)
Canavan disease is a rare autosomal recessive leukodystrophy characterized by abnormal accumulation of N-acetyl aspartate (NAA) in brain white matter. Currently, there is no cure for this disease, and management of patients consists mainly of treating symptoms. We describe a
Christopher G Janson et al.
Pediatric neurology, 33(4), 235-243 (2005-10-01)
Current evidence suggests that the effects of lithium on metabolic and signaling pathways in the brain may vary depending on the specific clinical condition or disease model. For example, lithium increases levels of cerebral N-acetyl aspartate in patients with bipolar
Treating PIK3CA and EGFR overexpressing breast cancers with lithium citrate.
Toni M Brand et al.
Cancer biology & therapy, 11(3), 368-370 (2011-01-14)

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico